中科院納米生物效應與安全性重點實驗室??
納米技術論壇?(CAS?NS?Forum?No.?399)??
第399期學術報告會通知??

演講者：Prof. Dan Larhammar?(Uppsala university, Sweden)
題??目：The usefulness of evolutionary thinking for neurobiology and neuropharmacology
時??間：2024年11月23日(星期六)，上午08:50
地??點：國家納米科學中心，新樓第六會議室
主持人：趙宇亮?院士

報告人簡介：Prof. Dan Larhammar，諾貝爾物理學、化學和經濟學獎委員會主席(2018-2021)，瑞典皇家科學院院士，原院長(2018-2021)，歐洲科學院院士，瑞典烏普薩拉大學教授。Dan Larhammar received his PhD degree in medical science at Uppsala University, Uppsala, Sweden, in 1984. He then studied neuropeptide Y (NPY), a multifunctional neuropeptide with strong stimulatory effect on appetite. After one year as visiting scientist at the Research Institute of Scripps Clinic in La Jolla, California, his work focused on cloning and molecular pharmacology of receptors for NPY. His laboratory discovered several NPY receptors. His research then broadened to exploration of the molecular evolution of verterate eyes; many of the differences between rods and cones in the retina can be explained by gene duplications resulting from the genome doublings at the origin of vertebrates. Numerous neurotransmitters and hormones and their receptors have been investigated with regard to their evolution in vertebrates. One project concerns the dopamine receptors involved in Parkinson's disease. Since several years he studies the molecular mechanisms for learning and long-term memory. Key players in this machinery are glutamate receptors of the AMPA and NMDA families and several proteins that regulate or are affected by these.

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